Sunday, March 6, 2016

Adverse Childhood Events and Subsequent Health Outcomes

In this study, information gleaned from a sample assessed during childhood and then subsequently followed in an adult health survey was used to assess adverse health outcomes associated with adverse childhood events (ACEs). Some studies have suggested that many adult health outcomes are associated with ACEs. For example, cardiovascular disease may have a higher risk in people exposed to ACEs as children. However, such associations are not fully confirmed. Most such studies are based on retrospective reports of ACEs, and retrospective recall is not very reliable. It is possible, for example, that people with more adverse health outcomes during adulthood are more likely to report or remember childhood adversities. Many of these studies have used clinical samples - and ACEs may affect health care use, which could distort the associations. If such associations exist (e.g. cardiovascular disease) it is likely that they occur through complex pathways, e.g. if ACEs increase the risk of depression, this may lead to higher rates of other behaviours (e.g. dietary and lifestyle factors) that may in turn increase the risk of cardiovascular disease. For these reasons, we recently sought to link survey that collected data from the same people during childhood and adulthood in representative community samples and to look at proximate changes that occur in relation to ACEs (i.e. changes that are evident in young adulthood). We found the most convincing evidence of associations for three inter-related outcomes and ACEs:  Major depression, psychotropic medication use and smoking. The abstract is available here. This study provides some insights into the early life impact of ACEs and suggests and smoking, especially, may be a link connecting ACEs to later health difficulties.

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